NAD+
Price range: $60.00 through $90.00
Coenzyme studied in cellular-energy and longevity research.
Description
A coenzyme present in every living cell, central to energy metabolism and electron transfer during cellular respiration. Research interest centers on its decline with age and its role in activating sirtuins and DNA-repair enzymes.
NAD+ is a dinucleotide coenzyme, not a peptide, and it does not behave like one on the shelf. It is more sensitive to heat, light and moisture than anything else in this catalogue, and reconstituted solution should be used promptly rather than held.
| Compound | beta-Nicotinamide adenine dinucleotide (oxidised form) |
|---|---|
| Also known as | NAD+, beta-NAD, NAD |
| Class | Dinucleotide coenzyme - not a peptide |
| Structure | An adenine nucleotide and a nicotinamide nucleotide joined through a pyrophosphate bridge. No amino-acid sequence applies. |
| Molecular formula | C21H27N7O14P2 (neutral form; databases also write the physiological cation as C21H28N7O14P2+) |
| Molecular weight | 663.4 g/mol (free acid) |
| CAS number | 53-84-9 (NAD+ free acid). Do not confuse with NADH (58-68-4), NADH disodium (606-68-8), beta-NAD sodium salt (20111-18-6) or NADP disodium (24292-60-2). |
| Appearance | White to off-white crystalline or lyophilised powder. |
| Purity specification | ≥98% |
Every lot ships against its own certificate of analysis. Search by lot number on the certificates of analysis page, or check the paperwork before you order.
NAD+ is supplied for laboratory research use only. It is not a drug, food or cosmetic, and it is not for human or veterinary use.
| Reconstitution | Freely water-soluble; bacteriostatic water or sterile water. |
|---|---|
| Storage, lyophilised | -20 °C, sealed and desiccated, protected from light and moisture. NAD+ is noticeably less stable than the peptides in this catalogue and degrades faster with heat and humidity. |
| Storage, reconstituted | 2-8 °C, protected from light, used promptly. Reconstituted NAD+ has a shorter practical life than a reconstituted peptide - plan on days rather than weeks. |
| Shipping | Shipped at ambient temperature. Lyophilised material tolerates transit without a cold chain; move it to the freezer on arrival. |
Working notes
- Let a vial come to room temperature before opening it. Opening a cold vial draws in moist air, and lyophilised powder takes up water quickly.
- Add the diluent slowly down the inside wall of the vial rather than directly onto the powder cake, and let it dissolve on its own. Shaking a peptide solution is the fastest way to denature it.
- Wipe the stopper with alcohol before every draw, and keep solutions out of direct light.
- Repeated freeze-thaw cycles cost you more purity than time in the fridge does. If a vial will be used over weeks, aliquot it once and freeze the aliquots.
Additional Information
| Size | 500mg, 1000mg |
|---|
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