TB-500 (Thymosin Beta-4 frag)
$80.00
Thymosin Beta-4 fragment studied in regeneration and recovery research.
Description
The acetylated seven-residue fragment of thymosin beta-4 (Ac-LKKTETQ), corresponding to the actin-binding region of that protein. It is not the full-length 43-residue protein, which is a separate molecule with a mass near 4963 Da; a correct TB-500 lot reports a mass close to 889 Da. Supplied as a lyophilised powder against a lot-specific certificate of analysis, for laboratory research use only.
TB-500 is the acetylated seven-residue fragment of thymosin beta-4, not the full-length 43-residue protein (which has its own CAS, 77591-33-4, and a mass near 4963 Da). A correct TB-500 certificate of analysis shows a mass close to 889 Da. Some suppliers also confuse TB-500 with Ac-SDKP, an unrelated tetrapeptide - Delta does not.
| Compound | TB-500 (thymosin beta-4 fragment 17-23) |
|---|---|
| Also known as | Ac-LKKTETQ, TB4 Frag 17-23 |
| Class | N-acetylated 7-residue peptide |
| Structure | Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH (Ac-LKKTETQ). N-terminally acetylated heptapeptide corresponding to the actin-binding region of thymosin beta-4. |
| Molecular formula | C38H68N10O14 |
| Molecular weight | 889.0 g/mol (free acid) |
| CAS number | 885340-08-9 |
| Appearance | White to off-white lyophilised powder. |
| Purity specification | ≥99% by HPLC |
Every lot ships against its own certificate of analysis. Search by lot number on the certificates of analysis page, or check the paperwork before you order.
TB-500 (Thymosin Beta-4 frag) is supplied for laboratory research use only. It is not a drug, food or cosmetic, and it is not for human or veterinary use.
| Reconstitution | Bacteriostatic water or sterile water. |
|---|---|
| Storage, lyophilised | -20 °C, sealed and desiccated, protected from light. |
| Storage, reconstituted | 2-8 °C, protected from light. Use within 2-4 weeks, or freeze single-use aliquots at -20 °C for longer holds. |
| Shipping | Shipped at ambient temperature. Lyophilised material tolerates transit without a cold chain; move it to the freezer on arrival. |
Working notes
- Let a vial come to room temperature before opening it. Opening a cold vial draws in moist air, and lyophilised powder takes up water quickly.
- Add the diluent slowly down the inside wall of the vial rather than directly onto the powder cake, and let it dissolve on its own. Shaking a peptide solution is the fastest way to denature it.
- Wipe the stopper with alcohol before every draw, and keep solutions out of direct light.
- Repeated freeze-thaw cycles cost you more purity than time in the fridge does. If a vial will be used over weeks, aliquot it once and freeze the aliquots.
Additional Information
| Size | 5mg, 10mg |
|---|
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